ABSTRACT
To determine the frequency and types of various ovarian teratomas amongst various age groups, and 2] To compare the results with other workers. Study Design: Retrospective study. The study was conducted at the Department of Pathology, Basic Medical Sciences Institute[BMSI], Jinnah Post graduate medical centre [JPMC], Karachi from 1[st] January 2001 to 31[st] December 2005. 1128 cases of ovarian biopsies were received for histopathological examination at the Department of Pathology, Basic Medical Science Institute, JPMC,Karachi.Out of 365 cases of ovarian neoplasms teratomas were separated, analyzed and classified according to the WHO classification system 1994 and their relative frequencies were recorded. Teratomas account for 14.52% [53/365] of all ovarian neoplasms. Mature cystic teratomas were the most common i.e 86.80% [46/53].Immature teratomas were 9.43% [05/53] followed by special subtypes 3.77% [02/53]. Mature cystic teratomas are the most common germ cell neoplasms of ovary. Immature teratomas are rare above 30 years of age
Subject(s)
Humans , Female , Teratoma , Retrospective Studies , Neoplasms, Germ Cell and EmbryonalABSTRACT
Gastric cancer is among the most common malignancies in Pakistan. The aim of our study are i] to document different histological types of gastric malignancies as per age and sex ii] discuss its possible association in patients who underwent endoscopy and iii] compare our data with local and abroad studies. Retrospective study. This study was conducted in the Department of Pathology, Basic Medical Science Institute, Jinnah Postgraduate Medical Centre, Karachi, Pakistan, from 1[st] January 2003 to 31 December 2007. A total of 740 cases of gastric endoscopic biopsies were received for histopathological evaluation at the Department of Pathology, Basic Medical Science Institute, JPMC, Karachi. Out of these cases, a total of 70 gastric neoplasms were separated, analyzed and classified according to the WHO classification system and their relative frequencies were recorded. Gastric adenocarcinoma was the commonest neoplasm with male predominance in 5th to 7[th] decade of life, account for 88.57% [62/70] of all gastric neoplasms. Gastric lymphoma was the second common with 8.57%[06/70] and gastric carcinoid was least common with 1.43%[1/70] of all gastric neoplasms. This study highlights that adenocarcinoma is the most common gastric malignancy seen in most high risk group includes elderly males followed by lymphoma with no gender difference. So we advise regular endoscopic biopsies surveillance at least in high risk age group for the early detection of cancer
ABSTRACT
To find out etiology and species identification of dermatophytes causing tinea cruris. Prospective study.This study was conducted in the Department of Microbiology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi from September 2000 to August, 2001. Ninety-five patients having skin infections [clinically suspected cases of tinea cruris] were examined. The skin scraping were taken from active border of the lesions and subjected to direct microscopy and culture on mycobiotic agar [Difco] for isolation of dermatophytes. Various special media were used for species identification. Tinea cruris was predominantly seen in adult [85.2%] than in adolescent [9.5%] and children [5.3%]. Out of 95 cases studied 83 [87.4%] were males and 12 [12.6%] were females. Tinea cruris was significantly found more in males [87.4%] than females [12.6%] [P < 0.001]. Regarding various species of dermatophytes, 38 [67.9%] cases were caused by Trichophyton rubrum, 14 [25%] by Epidermophyton floccosum and Trichophyton mentagrophytes 02 [3.5%]. Trichophyton violaceum and Trichophyton tonsurans accounted for the remaining 01 [1.8%] case respectively. Tinea cruris is a common problem of our population affecting predominantly male population. Different species like Trichophyton rubrum, Epidermophyton floccosum, Trichophyton mentagrophytes and Trichophyton violaceum and Trichophyton tonsurans is most commonly isolated from study group. It is proposed that a large sample size study with antifungal drugs sensitivity should be designed to get a more clear picture of dermatophytes involved in Tinea cruris
ABSTRACT
To observe the pattern of antibiotic resistance in methicillin sensitive and methicillin resistant staphylococcus aureus. Materials and Two hundred Staphylococcus aureus isolates from patients with hospital- acquired infections were collected. Methicillin resistance was determined by disc [oxacillin 1 micro g] diffusion method. Sensitivity to other antimicrobial agents was determined by Kirby Baurer disc diffusion method. The methicillin resistant Staphylococcus aureus isolates were found sensitive to vancomycin [100%], fusidic acid [88.5%], chloramphenicol [80.8%] and fosfomycin [61.5%]. All the isolates were highly resistant to other classes of antimicrobial agents. Methicillin resistant Staphylococcus aureus shows multi-drug resistance and infections caused by these isolates are difficult to treat. However our results show that beside vancomycin; fusidic acid, chloramphenicol and fosfomycin are good choices and should be tried for the isolates showing sensitivity to these agents